Flights From Buffalo (BUF) to Panama City (PTY)

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

Selected fares from Buffalo to Panama City

The cheapest prices found with in the last 7 days for return flights were CA $666 and CA $290 for one-way flights to Panama City for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Delta
American Airlines

Save more with Panama City Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Summit Rainforest & Golf Resort
Dreams Playa Bonita Panama - All Inclusive
Las Americas Golden Tower Panama
Central Hotel Panama Casco Viejo
Casa Contemporanea by Wynwood House
Hotel Riu Plaza Panama
Don't see what you're looking for?
See all available trips from Buffalo to Panama City
View all trips