Book Exclusive De Soto Vacation Packages

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De Soto flight + hotel packages

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Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
The Wildwood Hotel
Hilton Pennywell St. Louis at the Arch
The Last Hotel
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

De Soto Vacations

Experiencing the real essence of De Soto starts with researching a few basic facts. Are you ready to find out just where this unique destination is and what attractions you should explore?

You can find it 12 miles (19 kilometers) from Bonne Terre and 12 miles (19 kilometers) away from Festus.

Love meeting the locals when you're on vacation? This corner of Missouri has a population of around 6,000 people.

Places to visit in De Soto

Want to alleviate the stress of your busy, urban life? Drink in the fresh air as you take off on an adventure through St. Francois State Park. Want some more ideas? Are you looking to relieve the stress of your busy, urban life? Savor the fresh air as you embark on an adventure through Washington State Park.

Where do you fly into for De Soto?

Bags packed and passport at the ready? Excellent — hop on the plane to Spirit of St. Louis Airport (SUS). Once you hit the runway, you'll be just 40 miles (64 kilometers) from the main streets of De Soto.

Frequently asked questions

How much are vacation packages to De Soto?
Your travel daydreams can become a reality in De Soto from just CA $815. Our package deals include flights and hotels, so organizing your itinerary will be a piece of cake. The only thing you’ll have to concentrate on is getting out there and having a great time.
How long should my De Soto vacation be?
Many people choose to spend about 2 nights in De Soto, but how long you stay is your call. If you want to check out all the fantastic things this place offers, why not hang around a while longer?
Where can I get the best vacation package deals for De Soto?
Find your dream escape at Travelocity. With access to 400 airline partners and a whopping 1,000,000 hotels around the world, selecting the perfect De Soto package deal couldn’t be easier.
Why should I book my De Soto vacation package via Travelocity?
From enticing destinations to fun experiences, we have everything you need to satisfy your wanderlust. Our 24/7 support will also make sure you’re being taken care of before, during and after your vacation. And don’t stress if you spot a lower price on your booking, we’ll match it. That’s our Price Match Guarantee.
Can I save money on my De Soto car rental if I bundle it with a hotel or flight?
Combining your flight, hotel and car into a De Soto vacation package is a surefire way to land the best prices. Plus, having your own car rental gives you absolute freedom to find your way to all the landmarks you’re hoping to check out. Sitting 64 kilometers away from De Soto, Busch Stadium is one place that should have a place on your itinerary. Fasten your seat belt and make a day trip of it.
Which airport is best for De Soto?
Flying into De Soto will see you landing at Lambert-St. Louis Intl. Airport (STL). It’s roughly 72 kilometers north of the downtown area.
What is there to do in De Soto?
Victoria Glaces Conservation Area Trailhead deserves a spot on your travel itinerary. After you’ve checked off this well-known attraction, simply roam the streets of De Soto and learn what really makes this cool destination tick.
Where should I stay when visiting De Soto?
Many travelers choose to check in to the Holiday Inn Club Vacations Timber Creek Resort At De Soto. It’s a great base for your De Soto getaway.

Photos of local treasures

Browse De Soto vacation photos for more inspiration

Photo by Jessica King