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Book Exclusive Eastern Panama Vacation Packages
Eastern Panama flight + hotel packages
Price found within the past 48 hours. Click for updated prices.
![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/4b0d48d5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Villa Botero By Casa Mojito B&B
per person
May 7 - May 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.
![Residencia Natural](https://images.trvl-media.com/lodging/19000000/18280000/18277300/18277244/53ecf2c5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Residencia Natural
per person
Mar. 27 - Apr. 3
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Panama City (PTY)
Stay at this 3-star beach aparthotel in Bastimentos. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Bastimentos National Marine Park and Playa Larga are located nearby.
![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/7f210f49_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Central Hotel Panama Casco Viejo
Casco Viejo
per person
May 7 - May 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cinta Costera and Amador Causeway are located nearby.
![Hotel Panamonte](https://images.trvl-media.com/lodging/2000000/1750000/1745200/1745151/ffc5eed9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Hotel Panamonte
Save 100% on your flight
per person
May 7 - May 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
Stay at this 3.5-star hotel in Jaramillo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Boquete Community Players Theater and Events Center and Church of San Juan Bautista are located nearby.
![Punta Caracol Acqua Lodge](https://images.trvl-media.com/lodging/1000000/890000/889800/889730/a34ec6e6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Punta Caracol Acqua Lodge
Punta Caracol
Save 100% on your flight
per person
May 7 - May 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.
Top Eastern Panama hotels deals
![San Blas Paradise Private Cabins on Shipwreck Island - meals included](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Perro Island, Narganá, Guna Yala
The price is CA $322 per night
CA $322
CA $354 total
includes taxes & fees
15 Feb - 16 Feb
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attraction Museum of the Kuna Nation is located nearby.
Breakfast included
![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/3c4ffaaa_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón
The price is CA $206 per night
CA $206
CA $226 total
includes taxes & fees
16 Feb - 17 Feb
Stay at this 3-star hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.
Pool
Breakfast included
![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/b0fd1376_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island, Narganá, Guna Yala
The price is CA $299 per night
CA $299
CA $329 total
includes taxes & fees
15 Feb - 16 Feb
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attraction Museum of the Kuna Nation is located nearby.
Breakfast included
Restaurant
![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/01e98139_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Private Over the Water Cabin on San Blas Island
9.542876, -78.899058, Narganá, San Blas
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna Nation and Porvenir Museum are located nearby.
Breakfast included
Kitchen
![Konsenda San Blas](https://images.trvl-media.com/lodging/100000000/99080000/99079700/99079675/70973aae_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Konsenda San Blas
Llano Cartí Km 11, El Llano, Panamá Province
Free cancellation
Reserve now, pay when you stay
The price is CA $72 per night
CA $72
CA $79 total
includes taxes & fees
14 Feb - 15 Feb
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Breakfast included
Parking included
![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/1fc8ef4f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Ordovician Beach Resort
Isla Grande, Isla Grande, Colon
The price is CA $1,157 per night
CA $1,157
CA $1,273 total
includes taxes & fees
26 Feb - 27 Feb
Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.
On private beach
Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Cayos Holandeses
Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.
Museum of the Kuna Nation
You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals.
Porvenir Museum
You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.
Frequently asked questions
Photos of local treasures
Browse Eastern Panama vacation photos for more inspiration
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![Eastern Panama](https://mediaim.expedia.com/destination/1/482903472e1439a493a2dee83b010272.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)
![Eastern Panama](https://mediaim.expedia.com/destination/1/3d9eeb9430a538d415835dae66f32e6b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)
![Eastern Panama](https://mediaim.expedia.com/destination/1/e91e7dd2d90ea5b24911aac1bf6211b5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)
![Eastern Panama](https://mediaim.expedia.com/destination/1/af03951a059f7966fe092201856ba764.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)