Book Exclusive Seneca Vacation Packages

Choose one or more items to build your trip:

Seneca flight + hotel packages

Price found within the past 48 hours. Click for updated prices.
Hilton Greenville

Hilton Greenville

3.5 out of 5
per person
Jan. 30 - Feb. 2
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.
Hotel Hartness

Hotel Hartness

4 out of 5
per person
Jan. 30 - Feb. 2
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Stay at this 4-star spa hotel in Greenville. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Haywood Mall and Topgolf are located nearby.
Cambria Hotel Greenville

Cambria Hotel Greenville

3 out of 5
per person
Dec. 28 - Jan. 2
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Greenville (GSP)
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd, an IHG Hotel

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd, an IHG Hotel

3.5 out of 5
per person
Dec. 28 - Jan. 2
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Greenville (GSP)
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room service in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.

Top Seneca hotels deals

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Free cancellation
Reserve now, pay when you stay
The price is CA $152 per night
CA $152
CA $187 total
includes taxes & fees
18 Nov - 19 Nov
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Littlejohn Coliseum and Memorial Stadium are located nearby.
Pool
Hot tub
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Free cancellation
Reserve now, pay when you stay
The price is CA $156 per night
CA $156
CA $171 total
includes taxes & fees
18 Nov - 19 Nov
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Littlejohn Coliseum and Memorial Stadium are located nearby.
Breakfast included
Pet-friendly
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd, Seneca, SC
Free cancellation
Reserve now, pay when you stay
The price is CA $99 per night
CA $99
CA $109 total
includes taxes & fees
12 Dec - 13 Dec
Book a stay at this business-friendly motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attraction Keowee Reservoir is located nearby.
Pool
Breakfast included
Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
Free cancellation
Reserve now, pay when you stay
The price is CA $119 per night
CA $119
CA $145 total
includes taxes & fees
12 Dec - 13 Dec
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Keowee Reservoir and Littlejohn Coliseum are located nearby.
Pool
Breakfast included
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street, Seneca, SC
The price is CA $170 per night
CA $170
CA $187 total
includes taxes & fees
1 Dec - 2 Dec
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Keowee Reservoir and Littlejohn Coliseum are located nearby.
Pool
Breakfast included
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123, Seneca, SC
Free cancellation
Reserve now, pay when you stay
The price is CA $137 per night
CA $137
CA $150 total
includes taxes & fees
25 Nov - 26 Nov
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Keowee Reservoir and Littlejohn Coliseum are located nearby.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Blue Ridge Field

Explore the great outdoors at Blue Ridge Field, a lovely green space in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.

Blue Ridge Field

Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's lakeside or attend a sporting event.

Oconee County Library Seneca Branch

Seneca City Hall

After visiting Seneca City Hall, make a plan to see the other sights and activities in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.

Seneca City Hall

Seneca Vacations

Even if you're the most impulsive traveler, it's still a wise idea to find out a few things about Seneca before you go. Highlight it on your map, make a list of the things to do there and let the fun begin!

Seneca is a neighborhood in Anderson. To get there, travel 20 miles (32 kilometers) northwest of the center of town.

Ready to meet some of the locals? 27,000 people call Anderson home.

Places to visit in Seneca

Are you ready to head out into nature and have a bit of fun? The Anderson region is home to some fabulous activities to throw yourself into, such as cycling. If you're looking for more action, jump at the chance to go shore fishing too.

Where do you fly into for Seneca?

Admire the scenic views as you approach Greenville-Spartanburg International Airport (GSP). Collect your baggage, pass through security and you'll be around 45 miles (72 kilometers) east from the middle of Seneca.

Frequently asked questions

How much are vacation packages to Seneca?
Vacation packages, which include hotels and flights in Seneca, are priced from as little as CA $670. Turn your travel fantasies into reality and secure your dream vacation with Travelocity today.
How long should my Seneca vacation be?
If you’re looking for some guidance, most travelers spend around 2 nights in Seneca. But to discover the true spirit of this destination, stay a little longer. You’ll be able to explore more and really take in the local culture.
Where can I get the best vacation package deals for Seneca?
There’s no need to look any further than Travelocity. With 400 air carriers and 1,000,000 properties worldwide, it’s a breeze to put together a Seneca package deal that satisfies your wanderlust.
Why should I book my Seneca vacation package via Travelocity?
Because life is one amazing journey, and we’ve got everything you could hope for to help you along the way. With our first-rate service and Price Match Guarantee, you can book your trip with confidence. Plus, you can sleep easy while you’re on the road knowing we’re always available to chat via our round-the-clock support.
Will I save money on my Seneca car rental if I bundle it with a hotel or flight?
Bundling your car, hotel and flight into a Seneca vacation package is a great way to score an incredible deal. Plus, having your own car rental gives you freedom to find your way to all the landmarks you can’t wait to explore. Situated 137 kilometers from Seneca, Dollywood is one attraction that should be on your itinerary. Load up the car and make a day trip of it.
Which airport is best for Seneca?
For many wanderers, a trip to Seneca means passing through Greenville-Spartanburg Intl. Airport (GSP). This popular airport is 72 kilometers east of the city center. You could also jet into Asheville Regional Airport (AVL) (88 kilometers away from central Seneca) or Athens, GA (AHN-Ben Epps) (88 kilometers away from central Seneca).
Where should I stay when visiting Seneca?
Many visitors stay at the Lakeside Lodge Clemson. It’s a terrific base for your Seneca escape.

Photos of local treasures

Browse Seneca vacation photos for more inspiration

Photo by Cindy Keese
Photo by Cindy Keese