21C Museum Hotel St Louis

4.5 star property
4.5-star luxury hotel near Enterprise Center

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Massages
Bar (on property)
Dining
Indoor pool

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • Enterprise Center
    ‪8 min walk‬
  • St. Louis Union Station
    ‪12 min walk‬
  • Busch Stadium
    ‪18 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪26 min drive‬

Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 King Bed

  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Room (Bunk Bed)

  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Double Room, 2 Queen Beds

  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

Room, 1 King Bed, Corner

  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

Luxury Double Room, 2 Queen Beds

  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

Heart of St. Louis.Within a 10-minute walk of this Downtown West hotel, you'll find Enterprise Center and City Museum. Also, St. Louis Union Station is within half a mile (1 km) and Busch Stadium is within 2 miles (3 km).

What's nearby

  • City Museum - 6 min walk - 0.6 km
  • Enterprise Center - 8 min walk - 0.7 km
  • St. Louis Union Station - 12 min walk - 1.0 km
  • Busch Stadium - 18 min walk - 1.6 km
  • Gateway Arch - 4 min drive - 2.7 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

4.5-star luxury hotel near Enterprise Center
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Meeting rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Elevator
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

Languages

English

Similar properties

Property amenities

Family friendly

  • Indoor pool
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Entertainment

  • Flat-screen TV with premium digital channels

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in each accommodation.

Property Registration Number 832174967

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 770 out of 1061 reviews
Rating 8 - Good. 163 out of 1061 reviews
Rating 6 - Okay. 58 out of 1061 reviews
Rating 4 - Poor. 32 out of 1061 reviews
Rating 2 - Terrible. 38 out of 1061 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Holly

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Mar 2025

10/10 Excellent

Caroline

Liked: Cleanliness
Stayed 2 nights in Dec 2024

10/10 Excellent

Irna

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Stephan

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Alexander

Stayed 2 nights in Jan 2025

10/10 Excellent

Dimonica

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024

10/10 Excellent

Greg Phillip Beasley

Stayed 4 nights in Dec 2024

10/10 Excellent

Madison

Liked: Staff & service, property conditions & facilities
Stayed 1 night in Jan 2025

8/10 Good

Natalie

Stayed 2 nights in Dec 2024

8/10 Good

Raegan

Travelled with family, Travelled with family and small children
Liked: Staff & service, property conditions & facilities
Disliked: Cleanliness
Air filter in room looks like it hadn’t been changed since they built a place. Lights in room aren’t all working.
Stayed 1 night in Jan 2025

10/10 Excellent

regine

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Highly recommend!
Beautiful property! Loved the decor. The rooms we chose was large (2 beds) and comfortable. Very clean and modern. Great bar! Mason is a great bartender!
Stayed 1 night in Jan 2025

2/10 Terrible

Jacob

Disliked: Cleanliness, staff & service
Stayed 1 night in Dec 2024

10/10 Excellent

Victoria

Liked: Cleanliness, staff & service, property conditions & facilities
We love staying here because on top of being super nice, it’s an easy walk to a Blues game. Love the bar & the coffee shop on sight, also.
Stayed 1 night in Dec 2024

10/10 Excellent

Verified traveller

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024

10/10 Excellent

Monique

Stayed 2 nights in Dec 2024

10/10 Excellent

Bell

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Dec 2024

10/10 Excellent

Elizabeth

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love this concept and everything was great . Cool building , great food , lovely staff. Room was big. Best of St. Louis !
Stayed 1 night in Dec 2024

10/10 Excellent

Christopher

Travelled with family, Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024

10/10 Excellent

Denise

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great stay
Fabulous hotel, decor amazing, loved the museum, room was perfect
Stayed 1 night in Dec 2024

10/10 Excellent

Pearlie

Liked: Cleanliness, staff & service, property conditions & facilities
The museum
Stayed 1 night in Dec 2024

10/10 Excellent

Bryant

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was amazing and accommodating
Stayed 1 night in Dec 2024

10/10 Excellent

Madison

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel exceeded our expectations in every way. Check in was quick and easy with friendly hotel, museum, and wait staff. The property is beautiful. The rooms are incredibly clean and have a sleek, modern feel. I especially appreciate their efforts to make the hotel experience more sustainable with reclaimed materials, eco friendly amenities, and skipping out on cheap one-off products (travel size toiletries) for bottles that stay in the room and I assume are refilled rather than tossed when empty. The pool is a proper 25yard pool that you can swim laps in. The gym is extensive and is open 24 hours. Both place include water taps in case you work up a thirst. Steam rooms, a sauna, and waterfall showers are located near the pool. Overall this hotel is an incredible experience at a reasonable price. Perfect for a weekend getaway, a special occasion, or a holiday. I cannot recommend 21C hotels enough. My partner and I plan on visiting other locations in the future and will go out of our way to book with them when possible.
Stayed 1 night in Dec 2024

10/10 Excellent

Kyle

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Dec 2024

6/10 Okay

Symon

Stayed 1 night in Dec 2024

10/10 Excellent

David

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024