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21C Museum Hotel St Louis

4.5 star property
4.5-star luxury hotel near Enterprise Center

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Room, 1 King Bed, Corner
Lobby
In-room safe, desk, laptop workspace, blackout drapes
Indoor pool

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • Busch Stadium
    ‪14 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed)

Room (Bunk Bed)

  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Double Room, 2 Queen Beds

  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

  • City view
  • 30 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout drapes

Luxury Double Room, 2 Queen Beds

  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

Heart of St. Louis.Within a 10-minute walk of this Downtown West hotel, you'll find Enterprise Center and City Museum. Also, St. Louis Union Station is within half a mile (1 km) and Busch Stadium is within 2 miles (3 km).

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

4.5-star luxury hotel near Enterprise Center
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Meeting rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Elevator
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

Languages

English

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Property amenities

Family friendly

  • Indoor pool
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Entertainment

  • Flat-screen TV with premium digital channels

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in each accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 803 out of 1112 reviews
Rating 8 - Good. 173 out of 1112 reviews
Rating 6 - Okay. 63 out of 1112 reviews
Rating 4 - Poor. 33 out of 1112 reviews
Rating 2 - Terrible. 40 out of 1112 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Claudia

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel
Stayed 4 nights in Apr 2025

10/10 Excellent

Holly

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Mar 2025

10/10 Excellent

Demetrius, Carmel

Liked: Cleanliness, property conditions & facilities
Stayed 1 night in Feb 2025

10/10 Excellent

Shannon

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Jan 2025

10/10 Excellent

Mark

Stayed 1 night in Jan 2025

4/10 Poor

john

Travelled with partner
Liked: Cleanliness
Disliked: Staff & service
Fridge didnt work, no access to ice if you need it for your room, restaurant and bar super expensive. Late night staff was rude when our issues came up. Parking is supe expensive.
Stayed 2 nights in Jan 2025

10/10 Excellent

Verified traveller

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Jack, Chesterfield

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jan 2025

10/10 Excellent

Stenesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Parking can be improved.
Stayed 2 nights in Jan 2025

6/10 Okay

Courtney

Travelled with partner
Liked: Amenities, property conditions & facilities
Disliked: Cleanliness
I enjoyed cleaned room and everything about the room. I also enjoyed the pool area as well.
Stayed 4 nights in Jan 2025

4/10 Poor

Devin

Travelled with partner
Liked: Staff & service, amenities, property conditions & facilities
Disliked: Cleanliness
The past few stays with this hotel has gotten worse and worse. We used to stay here every month.
Stayed 1 night in Dec 2024

10/10 Excellent

Savannah

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Went for my birthday weekend and enjoyed every amenity! There is quite no other hotel Ive been to where it had something to enjoy for anytime of the day. Whether it was the good press cafe in the morning, a midday swim, a good cocktail from idol wolf, or a lookaloo around the free art museum on the 2nd floor or even a good exercise. The room was phenomenal with a great view of downtown stl!
Stayed 2 nights in Jan 2025

10/10 Excellent

Raven

Liked: Cleanliness, staff & service, property conditions & facilities
It was such cool place! The pool and spa were so fun and Good Press was great for breakfast.
Stayed 2 nights in Jan 2025

10/10 Excellent

Todd, Lake St Louis

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jan 2025

8/10 Good

Monir

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the look and people!!
Stayed 2 nights in Dec 2024

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

4/10 Poor

Audrey

Travelled with group
Disliked: Cleanliness, property conditions & facilities
First checked in for my birthday weekend and they didn’t have my room ready until 8:30 PM when check in was at 4. They put us in a temporary room which was a room for one person when we had 4 and which had not been cleaned and other items of other peoples stuff were in there. Only stayed for one night and it ruined the whole reason of a doing a girls night in stl. The front desk was very honest so I appreciated that but she thought I was someone that she checked in and had an attitude at the beginning and I had to let her know that she needed to look up my account before assuming who I was. This was for my birthday and I thought this was going to be the best night but the staff and hotel just made it such a horrible experience for me. I actually started crying with the way they did everything. Just super disappointed because with the right staff and training this hotel could easily be 5 star hotel. I do want to put in here though that the valet parking crew was incredibly nice though and seem to really care.
Stayed 1 night in Jan 2025

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities
We stayed here after the Kody Johnson concert. Quick, convenient walk.
Stayed 1 night in Jan 2025

8/10 Good

Kenneth, Normal

Stayed 1 night in Jan 2025

10/10 Excellent

Bryan Rachel Caughran

Travelled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Outstanding place, just need a vending machine for snacks.
Stayed 1 night in Jan 2025

10/10 Excellent

Bailey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Convenient & Clean

Beautiful hotel with a perfect location! Staff was very friendly and vallet was so fast!
Stayed 1 night in Jan 2025

10/10 Excellent

Tylyn

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Super nive4 place little pricy for food but the food is worth it and love the museum and the drinks again a little pricy but is a great time and the staff are so friendly.
Stayed 1 night in Nov 2024

10/10 Excellent

CRISTINA

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jan 2025

8/10 Good

David

Liked: Cleanliness
Stayed 5 nights in Jan 2025

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025