Cheap Flights From McGhee Tyson (TYS) To San Diego Intl. (SAN)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

Find The Best Dates To Fly

Cheapest Flights from Knoxville (TYS) to San Diego (SAN)

The cheapest flights to San Diego Intl. found within the past 7 days were CA $507 round trip and one way. Prices and availability subject to change. Additional terms may apply.

Sat, Aug. 23 - Sat, Aug. 30
TYS
Knoxville
SAN
San Diego
CA $507 Roundtrip, found 6 days ago
CA $507
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Aug. 23 from Knoxville to San Diego, returning Sat, Aug. 30, priced at CA $507 found 6 days ago
Thu, Aug. 21 - Mon, Aug. 25
TYS
Knoxville
SAN
San Diego
CA $526 Roundtrip, found 4 days ago
CA $526
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Thu, Aug. 21 from Knoxville to San Diego, returning Mon, Aug. 25, priced at CA $526 found 4 days ago
Thu, Aug. 21 - Mon, Aug. 25
TYS
Knoxville
SAN
San Diego
CA $533 Roundtrip, found 4 days ago
CA $533
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Thu, Aug. 21 from Knoxville to San Diego, returning Mon, Aug. 25, priced at CA $533 found 4 days ago
Thu, Aug. 21 - Mon, Aug. 25
TYS
Knoxville
SAN
San Diego
CA $540 Roundtrip, found 4 days ago
CA $540
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Thu, Aug. 21 from Knoxville to San Diego, returning Mon, Aug. 25, priced at CA $540 found 4 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $545 Roundtrip, found 6 days ago
CA $545
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $545 found 6 days ago
Sat, Aug. 23 - Sat, Aug. 30
TYS
Knoxville
SAN
San Diego
CA $580 Roundtrip, found 6 days ago
CA $580
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Aug. 23 from Knoxville to San Diego, returning Sat, Aug. 30, priced at CA $580 found 6 days ago
Sat, Aug. 23 - Sat, Aug. 30
TYS
Knoxville
SAN
San Diego
CA $587 Roundtrip, found 6 days ago
CA $587
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Aug. 23 from Knoxville to San Diego, returning Sat, Aug. 30, priced at CA $587 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $600 Roundtrip, found 6 days ago
CA $600
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $600 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $618 Roundtrip, found 6 days ago
CA $618
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $618 found 6 days ago
Sat, Aug. 23 - Sat, Aug. 30
TYS
Knoxville
SAN
San Diego
CA $655 Roundtrip, found 6 days ago
CA $655
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Aug. 23 from Knoxville to San Diego, returning Sat, Aug. 30, priced at CA $655 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $672 Roundtrip, found 6 days ago
CA $672
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $672 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $686 Roundtrip, found 6 days ago
CA $686
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $686 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $695 Roundtrip, found 6 days ago
CA $695
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $695 found 6 days ago
Thu, Aug. 21 - Mon, Aug. 25
TYS
Knoxville
SAN
San Diego
CA $711 Roundtrip, found 4 days ago
CA $711
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Thu, Aug. 21 from Knoxville to San Diego, returning Mon, Aug. 25, priced at CA $711 found 4 days ago
Thu, Aug. 21 - Mon, Aug. 25
TYS
Knoxville
SAN
San Diego
CA $718 Roundtrip, found 4 days ago
CA $718
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Thu, Aug. 21 from Knoxville to San Diego, returning Mon, Aug. 25, priced at CA $718 found 4 days ago
Sat, Aug. 23 - Sat, Aug. 30
TYS
Knoxville
SAN
San Diego
CA $722 Roundtrip, found 6 days ago
CA $722
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Aug. 23 from Knoxville to San Diego, returning Sat, Aug. 30, priced at CA $722 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $741 Roundtrip, found 6 days ago
CA $741
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $741 found 6 days ago
Sat, Aug. 23 - Sat, Aug. 30
TYS
Knoxville
SAN
San Diego
CA $751 Roundtrip, found 6 days ago
CA $751
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sat, Aug. 23 from Knoxville to San Diego, returning Sat, Aug. 30, priced at CA $751 found 6 days ago
Tue, Oct. 14 - Mon, Oct. 20
TYS
Knoxville
SAN
San Diego
CA $766 Roundtrip, found 6 days ago
CA $766
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Tue, Oct. 14 from Knoxville to San Diego, returning Mon, Oct. 20, priced at CA $766 found 6 days ago
Thu, Aug. 21 - Mon, Aug. 25
TYS
Knoxville
SAN
San Diego
CA $775 Roundtrip, found 4 days ago
CA $775
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Thu, Aug. 21 from Knoxville to San Diego, returning Mon, Aug. 25, priced at CA $775 found 4 days ago

Frequently asked questions

Are there direct flights from TYS to San Diego Airport?
Unfortunately, there aren't any direct flights from McGhee Tyson Airport (TYS) to SAN. But there are airlines offering flights with only one stopover. Consider American Airlines, United Airlines and Delta.
What airlines fly from McGhee Tyson Airport (TYS) to SAN?
With no direct flights between Knoxville Airport and San Diego Airport, you will have at least one stopover. Best to plan ahead in order to book the quickest route and save some time.
What is the best day to buy a plane ticket?
Airfares offered on Friday tend to be the cheapest, according to flight demand on Travelocity.ca in 2021. Purchasing your airfares on a Thursday or Saturday can also provide better value, however our advice if you're looking to save money is to avoid booking on a Wednesday or Sunday. Our data shows that those two days have the highest ticket values on average, so keep this in mind if you're browsing flight deals.
What are the cheapest days to fly?
Frequent travellers may already know this, but earlier in the week is often the cheapest time to fly. Flights departing on a Monday are the cheapest of the week. Since flights towards the middle of the week tend to be more popular, this causes the prices to rise. This is why, on average, airfares booked on Travelocity.ca in 2021 were most expensive for Wednesday departures.
How far in advance can you book a flight?
Here's the deal: It is typically possible to start comparing international airfares on Travelocity.ca up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 2-4 weeks prior to their travel dates.*According to flight demand on Travelocity.ca from January to December 2021. Savings are subject to change and may vary depending on selections made.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.