
Cheap Flights From Buffalo Niagara Intl. (BUF) To San Diego Intl. (SAN)
Wander Wisely with exceptional service, 24/7 supportOpens in a new window
Feel at ease with free flight cancellations within 24 hours of booking
Change your flight without a fee on select flights
Find The Best Dates To Fly
Cheapest Flights from Buffalo (BUF) to San Diego (SAN)
The cheapest flights to San Diego Intl. found within the past 7 days were CA $386 round trip and CA $208 one way. Prices and availability subject to change. Additional terms may apply.
BUF
Buffalo
SAN
San Diego
CA $386 Roundtrip, found 4 days ago
CA $386
Roundtrip
found 4 days ago
BUF
Buffalo
SAN
San Diego
CA $387 Roundtrip, found 3 days ago
CA $387
Roundtrip
found 3 days ago
BUF
Buffalo
SAN
San Diego
CA $387 Roundtrip, found 4 days ago
CA $387
Roundtrip
found 4 days ago
BUF
Buffalo
SAN
San Diego
CA $388 Roundtrip, found 2 days ago
CA $388
Roundtrip
found 2 days ago
BUF
Buffalo
SAN
San Diego
CA $390 Roundtrip, found 2 days ago
CA $390
Roundtrip
found 2 days ago
BUF
Buffalo
SAN
San Diego
CA $440 Roundtrip, found 4 days ago
CA $440
Roundtrip
found 4 days ago
BUF
Buffalo
SAN
San Diego
CA $444 Roundtrip, found 3 days ago
CA $444
Roundtrip
found 3 days ago
BUF
Buffalo
SAN
San Diego
CA $445 Roundtrip, found 6 days ago
CA $445
Roundtrip
found 6 days ago
BUF
Buffalo
SAN
San Diego
CA $453 Roundtrip, found 3 days ago
CA $453
Roundtrip
found 3 days ago
BUF
Buffalo
SAN
San Diego
CA $456 Roundtrip, found 5 days ago
CA $456
Roundtrip
found 5 days ago
San Diego Intl. flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.





Don't see what you're looking for?
See all available trips from Buffalo Niagara Intl. to San Diego Intl.
View all tripsFrequently asked questions
Popular Flight Routes from Buffalo (BUF)
Travelers at BUF love to visit these top cities. Roam to the top destinations from Buffalo (BUF) today with the cheap prices from Travelocity!
Popular Flight Routes from San Diego (SAN)
Travelers at SAN love to visit these top cities. Roam to the top destinations from San Diego(SAN) today with the cheap prices from Travelocity!
Top Airlines Routes From BUF
- JetBlue Airways Buffalo to Los Angeles
- JetBlue Airways Buffalo to Tampa
- JetBlue Airways Buffalo to Fort Lauderdale
- JetBlue Airways Buffalo to Boston
- Delta Buffalo to New York
- Etihad Airways Buffalo to Delhi
- JetBlue Airways Buffalo to New York
- Delta Buffalo to Dallas
- American Airlines Buffalo to Dallas
- JetBlue Airways Buffalo to Philadelphia
Top Airlines Routes To SAN
- WestJet Ottawa to San Diego
- WestJet Calgary to San Diego
- Alaska Airlines Kelowna to San Diego
- Alaska Airlines Detroit to San Diego
- WestJet Saskatoon to San Diego
- WestJet Winnipeg to San Diego
- WestJet Halifax to San Diego
- Alaska Airlines Victoria to San Diego
- Alaska Airlines Seattle to San Diego
- Alaska Airlines Vancouver to San Diego
Most Popular
Flights
YEG - SNAYVR - PSPYVR - LASDTW - DFWYEG - LAXYUL - FLLJFK - YYZBUF - JFKYYZ - LAXYYZ - SFOYYZ - JFKYVR - SFOYVR - SANDTW - MYRYYZ - SEAYYZ - SNAYYZ - DFWAir Canada Toronto (YYZ) to Myrtle Beach (MYR) flightsSpirit Airlines Niagara Falls (IAG) to Myrtle Beach (MYR) flightsJetBlue Airways Buffalo (BUF) to Fort Lauderdale (FLL) flightsPorter Airlines Toronto (YTZ) to Philadelphia (PHL) flightsYVR - LAXYYJ - LAXYYZ - LGAAir Canada Toronto (YYZ) to Fort Lauderdale (FLL) flightsYVR - SNAYYZ - LASSwoop Abbotsford (YXX) to Las Vegas (LAS) flightsYVR - JFKSEA - DEL