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Most frequently booked O Brien hotels
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Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
14.67 km from city centre
Book a stay at this family-friendly vacation home in O Brien. Enjoy free WiFi, a beach locale, and a garden. Popular attractions Wes Skiles Peacock Springs State Park and Telford Spring are located nearby.
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Pet-Friendly Florida Escape w/ Patio & Fire Pit!
14.14 km from city centre
Book a stay at this family-friendly vacation home in O Brien. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions Ichetucknee River and Ichetucknee Springs State Park are located nearby.
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MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
14.76 km from city centre
The price is CA $282 per night
CA $282
CA $605 total
includes taxes & fees
5 Mar - 6 Mar
Stay at this vacation home in O Brien. Enjoy a garden, patios, and cable/satellite TV service. Popular attractions Wes Skiles Peacock Springs State Park and Telford Spring are located nearby.
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La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE, Lake City, FL
Free cancellation
Reserve now, pay when you stay
29.33 km from city centre
The price is CA $144 per night
CA $144
CA $162 total
includes taxes & fees
24 Feb - 25 Feb
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Lake City Mall and Southside Recreation Complex are located nearby.
Pool
Breakfast included
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Americas Best Value Inn Lake City
3835 West US Highway 90, Lake City, FL
Free cancellation
Reserve now, pay when you stay
28.42 km from city centre
The price is CA $101 per night
CA $101
CA $114 total
includes taxes & fees
2 Mar - 3 Mar
Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Lake City Mall and Southside Recreation Complex are located nearby.
Pool
Breakfast included
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TownePlace Suites by Marriott Lake City
178 NW COMMERCE DR, Lake City, FL
Free cancellation
Reserve now, pay when you stay
29.16 km from city centre
The price is CA $190 per night
CA $190
CA $214 total
includes taxes & fees
2 Mar - 3 Mar
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lake City Mall and Southside Recreation Complex are located nearby.
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Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel
16367 NW 167TH BLVD, Alachua, FL
Free cancellation
48.16 km from city centre
The price is CA $201 per night
CA $201
CA $226 total
includes taxes & fees
2 Mar - 3 Mar
Stay at this 3.5-star business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Alachua Sports Complex and City of Alachua Recreation and Community Center are located nearby.
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Best Western Plus Lake City
350 SW Florida Gateway Dr, Lake City, FL
Free cancellation
Reserve now, pay when you stay
28.81 km from city centre
The price is CA $170 per night
CA $170
CA $192 total
includes taxes & fees
23 Feb - 24 Feb
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Lake City Mall and Southside Recreation Complex are located nearby.

Holiday Inn & Suites Lake City, an IHG Hotel
213 Sw Commerce Dr, Lake City, FL
Free cancellation
29.15 km from city centre
The price is CA $167 per night
CA $167
CA $188 total
includes taxes & fees
2 Mar - 3 Mar
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Lake City Mall and Southside Recreation Complex are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top hotels in O Brien for Extended Stay
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Experience the Best Hospitality in Lake City!
Lake City
The price is CA $130 per night from Mar. 3 to Mar. 4
CA $130
CA $175 total
includes taxes & fees
3 Mar - 4 Mar
5.4/10 (3 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
O Brien hotels essential information
Accommodation | 305 hotels |
---|---|
Lowest Price | CA $101 |
Highest Price | CA $282 |
Popular hotels | Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!, Pet-Friendly Florida Escape w/ Patio & Fire Pit!, MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY, La Quinta Inn & Suite by Wyndham Lake City, Americas Best Value Inn Lake City, TownePlace Suites by Marriott Lake City, Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel, Best Western Plus Lake City, Holiday Inn & Suites Lake City, an IHG Hotel |
Frequently asked questions
Recent O Brien hotel reviews by fellow wanderers
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Americas Best Value Inn Lake City
5 out of 5
Posted 22 hours ago
Travelocity Verified Review
"Amazing for the price
Professional, Friendly service
Would stay here anytime in the area"
A verified traveller stayed at Americas Best Value Inn Lake City
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