Book spa resorts in Florence, SC from CA $147
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Top Florence Spa Resorts & Hotels
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
Free cancellation
The price is CA $152 per night
CA $152
CA $170 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hampton Inn & Suites Florence Center
3000 W Radio Dr Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $132 per night
CA $132
CA $147 total
Dec 21 - Dec 22
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Free cancellation
Reserve now, pay when you stay
The price is CA $242 per night
CA $242
CA $272 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $147 per night
CA $147
CA $165 total
Jan 6 - Jan 7, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $180 per night
CA $180
CA $202 total
Jan 8 - Jan 9, 2026
includes taxes & fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $132 per night
CA $132
CA $147 total
Dec 25 - Dec 26
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hilton Garden Inn Florence
2671 Hospitality Boulevard Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $137 per night
CA $137
CA $154 total
Dec 14 - Dec 15
includes taxes & fees
Book a stay at this family-friendly hotel in Florence. Enjoy room service, a fitness center, and a garden. Our guests praise the helpful staff in our reviews. ...
SpringHill Suites by Marriott Florence
2670 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $146 per night
CA $146
CA $164 total
Dec 10 - Dec 11
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Florence
2680 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $134 per night
CA $134
CA $150 total
Dec 15 - Dec 16
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Florence Spa Hotels
There is nothing more refreshing than a day at the spa. And the pure joy of spa hotels in Florence will make you feel rejuvenated and relaxed. Pamper yourself while in Florence with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Florence offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Florence spa hotel and prepare to relax.
Florence hotels essential information
Accommodation | 367 hotels |
|---|---|
Lowest Price | CA $147 |
Highest Price | CA $272 |
Popular hotels | Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG, Courtyard by Marriott Florence, Hampton Inn & Suites Florence Center, Hampton Inn & Suites Florence-North-I-95, Hilton Garden Inn Florence, Hotel Florence, Tapestry Collection by Hilton, Residence Inn Marriott Florence, SpringHill Suites by Marriott Florence, The Mantissa Hotel |
Recent Florence hotel reviews by fellow wanderers
Residence Inn Marriott Florence
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"I loved everything about it "
A verified traveller stayed at Residence Inn Marriott Florence
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