
Book Cheap Delta flight from Detroit (DTW) to St. Louis (STL) from CA $295
Find The Best Day to Book a Cheap Delta Flights From Detroit to St. Louis
Cheapest Delta Flights from Detroit (DTW) to St. Louis (STL)
The cheapest flights to Lambert-St. Louis Intl. found within the past 7 days were CA $477 round trip and CA $295 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Grab a great Delta flight from DTW to STL
To find a great deal on Delta flights with Travelocity, simply enter your origin and destination airports, pick your travel dates, and hit search. From here, you can sort by price, flight duration, and arrival/departure time. You can also filter to find nonstop flights.
Flying Delta Detroit to St. Louis gives you fights to choose from. With that direct flight time of , you’ll be touching down before you know it.
Find cheap flights with Delta between Detroit and St. Louis
Delta has a range of great fares on stacks of flights, and to find the most affordable for you, there are a few tricks you can try. Booking in advance, for example, is a great way to grab a fantastic deal. Also, choose the cheapest month, if you can. One-way flights from Detroit to St. Louis with Delta are March.
The more flexible you are, the more affordable flights you’re likely to find. Consider one-way flights and connecting flights, as well as standard roundtrip and direct options. Even if you’re flying today, cheap last-minute flights are easy to find by entering your travel dates and hitting search.
Reasons to book your Delta flights with Travelocity
Travelocity makes it easy to book a seat, anywhere in the world. The vast inventory, fast search, and advanced filters put some of the best deals on the planet in one place. Whether you’re traveling on business, with friends, family, or on your own, take your pick from some fantastic options. And with free cancellation and pay later options, you can travel more and worry less.
Airport code | Country | Airport name | Number of flights |
|---|---|---|---|
| ATL | USA | Hartsfield-Jackson Atlanta Intl. | 252 |
| DTW | USA | Detroit Metropolitan Wayne County | 156 |
| MSP | USA | Minneapolis - St. Paul Intl. | 131 |
| SLC | USA | Salt Lake City Intl. | 116 |
| SEA | USA | Seattle - Tacoma Intl. | 57 |
| LAX | USA | Los Angeles Intl. | 41 |
| AMS | NLD | Schiphol | 31 |
| YYC | CAN | Calgary Intl. | 26 |
| YYZ | CAN | Pearson Intl. | 24 |
| JFK | USA | John F. Kennedy Intl. | 23 |
Travelers ❤️ these 🏨 after their flight to St. Louis

Pear Tree Inn St. Louis Airport
Hotel is very clean and staff is very attentive, very caring and courteous. Shuttle bus to and from the Airport (ST Louis Lambert) is really good to have. They are very prompt and take care of you. I would recommend this hotel without a doubt. Very convenient, very clean and breakfast and location ...
Reviewed on Dec 21, 2025

Renaissance St. Louis Airport Hotel
Room was
Reviewed on Dec 13, 2025

Hilton St. Louis Airport
I like the remodel of the lobby and lounge areas. The room was as expected. Check in was fairly easy at the desk and staff was polite.
Reviewed on Dec 18, 2025
Want more than a(n) Delta Flight from Detroit to St. Louis?
Popular Delta Flight Routes from DTW
Top Delta Flight Routes from STL
Domestic
- Vancouver to Las Vegas (YVR - LAS)
- Toronto to Fort Lauderdale (YYZ - FLL)
- Toronto to Mumbai (YYZ - BOM)
- Calgary to Delhi (YYC - DEL)
- Toronto to Las Vegas (YYZ - LAS)
- Montreal to Cancun (YUL - CUN)
- Montreal to Las Vegas (YUL - LAS)
- Vancouver to Delhi (YVR - DEL)
- Toronto to Delhi (YYZ - DEL)
- Toronto to Orlando (YYZ - MCO)
International
- Calgary to Delhi (YYC - DEL)
- Calgary to Delhi (YYC - DEL)
- Toronto to Cairo (YYZ - CAI)
- Vancouver to Delhi (YVR - DEL)
- Vancouver to Las Vegas (YVR - LAS)
- Montreal to Fort Lauderdale (YUL - FLL)
- Vancouver to Delhi (YVR - DEL)
- Winnipeg to Delhi (YWG - DEL)
- Toronto to Orlando (YYZ - MCO)
- Montreal to Las Vegas (YUL - LAS)
Most Popular
- YVR - PSP
- YVR - LAS
- DTW - DFW
- WestJet Vancouver (YVR) to Las Vegas (LAS) flights
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- YUL - FLL
- BUF - DFW
- YVR - FLL
- Delta Detroit (DTW) to Las Vegas (LAS) flights
- BUF - MYR
- DTW - FLL
- FLL - YYZ
- YVR - SAN
- DTW - MYR
- YYZ - SEA
- YVR - DFW
- YYZ - DFW
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- Spirit Airlines Niagara Falls (IAG) to Myrtle Beach (MYR) flights
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- YYZ - LAS
- WestJet Calgary (YYC) to Seattle (SEA) flights
- Swoop Abbotsford (YXX) to Las Vegas (LAS) flights
- WestJet Toronto (YYZ) to Columbia (COU) flights
- Air Canada Toronto (YYZ) to San Diego (SAN) flights
- Delta Buffalo (BUF) to Las Vegas (LAS) flights
- SEA - DEL
