Book spa resorts in Big Pine Key, FL

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Top Big Pine Key Spa Resorts & Hotels

Deer Run Bed & Breakfast

1997 Long Beach Road, Big Pine Key, FL

Book a stay at this beach B&B in Big Pine Key. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Bahia Honda State Park and Coupon Bight ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

There is nothing more refreshing than a day at the spa. And the pure joy of spa hotels in Big Pine Key will make you feel rejuvenated and relaxed. Pamper yourself while in Big Pine Key with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Big Pine Key offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Big Pine Key spa hotel and prepare to relax.