Defiance Vacations 2025 from CA $745

Defiance flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel

per person

May 2 - May 4

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Skid Row and Hidden Valley Ski Resort are located nearby.

Hilton Garden Inn Chesterfield

per person

Apr. 17 - Apr. 24

found 1 day ago

Roundtrip flight included

St. John's (YYT) to St. Louis (STL)

Stay at this 3-star business-friendly hotel in Chesterfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Topgolf and Taubman Prestige Outlets are located nearby.

Moonrise Hotel

West End

per person

Apr. 17 - Apr. 24

found 1 day ago

Roundtrip flight included

St. John's (YYT) to St. Louis (STL)

Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.

The Cheshire

per person

Apr. 17 - Apr. 24

found 1 day ago

Roundtrip flight included

St. John's (YYT) to St. Louis (STL)

Stay at this 4-star boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Louis Union Station and St. Louis Zoo are located nearby.

HoteLumiere at the Arch

Downtown St. Louis

per person

May 2 - May 4

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular attractions St. Louis Union Station and Dome at America’s Center are located nearby.

Popular places to visit

St. Louis Union Station

4.5/5(7 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

St. Louis Zoo

4.5/5(7 reviews)

Why not visit the native and exotic animals who live at St. Louis Zoo during your trip to St. Louis? Amble around the area's lush forest or attend a sporting event.

Defiance Vacations

Before you fly off to Defiance on a whim, take the time to learn a few facts about it.

Around 30 miles (48 kilometers) to the west of downtown St. Louis, Defiance is one of the neighborhoods that make this city so appealing.

At last count, the population of St. Louis was 320,000.

Places to visit in Defiance

The St. Louis region offers plenty of opportunities for outdoor adventures. Why not go rock climbing while you're here? If you'd like to double the fun factor, also make plans to go caving.

Where do you fly into for Defiance?

Fasten your seatbelt and get ready to touch down at Spirit of St. Louis Airport (SUS). This is the closest major terminal and it's approximately 9 miles (14 kilometers) to the east from the center of Defiance. Collect your luggage and let the fun begin!

Frequently asked questions

How much are vacation packages to Defiance?

Treat yourself to a one-of-a-kind experience in Defiance with a vacation package starting from just CA $745. Organizing your hotels, tours and flights with Travelocity is a piece of cake. What’s more, our vacation deals will leave you with extra cash for loads of fun times.

Where can I get the best vacation package deals for Defiance?

It’s difficult to beat Travelocity when it comes to piecing together your Defiance package deal. There are as many as 400 partner airlines and 1,000,000 properties around the world to choose from. Secure your trip now and get ready to cross another amazing place off your travel bucket list.

Why should I purchase my Defiance vacation package with Travelocity?

From our 24/7 customer care to our range of fantastic destinations, we’re committed to fulfilling your travel desires. All you’ll have to do is click and book — our Price Match Guarantee will make sure you score the best price.

Can I save on my Defiance car rental if I bundle it with my hotel or flight?

With a Defiance vacation package, you can bundle your hotel, car and flight bookings and save some serious money. If you’d love to discover the best of this wonderful part of the world, why not head to Busch Stadium? This popular attraction is 48 kilometers from Defiance. With your own rental car, you’ll be there before you know it.

Which airport is best for Defiance?

Lambert-St. Louis Intl. Airport (STL) is the top airport for those flying to Defiance. Once you touch down, you’ll find yourself 40 kilometers east of the downtown area.

What is there to do in Defiance?

There is a certain magic in the air as you stroll the streets of Defiance. Chandler Hill Vineyards and Historic Daniel Boone Home and Heritage Center are just two famous sights that make this city so popular, so put them at the top of your must-see list.

Where should I stay when visiting Defiance?

The BACKYARD OASIS! Cozy and charming 60s Brick ranch with relaxing gazebo over pond is recommended by many travelers. Book soon to avoid missing out.