Book luxury hotels in Florida Keys

Name: Southernmost Beach Resort
Price range: CA $340
Rating: 8.4

Top Florida Keys Luxury Hotels

Little Palm Island Resort & Spa - A Noble House Resort

28500 Overseas Hwy, Summerland Key, FL

Get rates

Stay at this 5-star luxury resort in Summerland Key. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Big Pine Key Flea Market and ...

H2O Suites - Adults Only

1212 Simonton Street, Key West, FL

CA $501

CA $626 total

includes taxes & fees

19 Dec - 20 Dec

Stay at this 3.5-star business-friendly hotel in Key West. Enjoy free WiFi, a rooftop terrace, and a fitness center. Our guests praise the pool and the helpful ...

The Mansion on the Sea - Southernmost House in the USA

1400 Duval Street, Key West, FL

CA $627

CA $748 total

includes taxes & fees

26 Nov - 27 Nov

Stay at this 3-star beach hotel in Key West. Enjoy free breakfast, room service, and parking (surcharge). Our guests praise the helpful staff and the property ...

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL

Free cancellation

Reserve now, pay when you stay

CA $418

CA $564 total

includes taxes & fees

22 Nov - 23 Nov

Stay at this 5-star luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West, FL

Free cancellation

Reserve now, pay when you stay

CA $250

CA $363 total

includes taxes & fees

2 Dec - 3 Dec

Stay at this 4-star golf hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...

The Marker Key West Harbor Resort

200 William Street, Key West, FL

Free cancellation

Reserve now, pay when you stay

CA $350

CA $478 total

includes taxes & fees

1 Dec - 2 Dec

Stay at this 4-star eco-certified hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and breakfast (surcharge). Our guests praise the pool and the bar in our ...

Parmer's Resort

565 Barry Avenue, Summerland Key, FL

Free cancellation

Reserve now, pay when you stay

CA $151

CA $215 total

includes taxes & fees

3 Dec - 4 Dec

Book a stay at this beach motel in Summerland Key. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Playa Largo Resort & Spa, Autograph Collection

97450 Overseas Highway, Key Largo, FL

Free cancellation

Reserve now, pay when you stay

CA $431

CA $562 total

includes taxes & fees

4 Dec - 5 Dec

Stay at this 4.5-star luxury resort in Key Largo. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...

Southernmost Beach Resort

1319 Duval Street, Key West, FL

Free cancellation

Reserve now, pay when you stay

CA $340

CA $476 total

includes taxes & fees

17 Dec - 18 Dec

Stay at this 4-star beach hotel in Key West. Enjoy 3 outdoor pools, a full-service spa, and a beach locale. Our guests praise the pool and the bar in our reviews. ...

Kingsail Resort

7050 Overseas Highway, Marathon, FL

CA $156

CA $175 total

includes taxes & fees

8 Dec - 9 Dec

Stay at this motel in Marathon. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...

Seashell Motel & Key West Hostel

718 South Street, Key West, FL

Free cancellation

Reserve now, pay when you stay

CA $167

CA $188 total

includes taxes & fees

24 Nov - 25 Nov

Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street, Key West, FL

Free cancellation

Reserve now, pay when you stay

CA $407

CA $546 total

includes taxes & fees

8 Dec - 9 Dec

Stay at this 5-star luxury resort in Key West. Enjoy 2 outdoor pools, a full-service spa, and a private beach. Popular attractions Duval Street and Mallory Square ...

Don't see what you're looking for?

See all available properties in Florida Keys

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

If you’re looking for a luxury vacation in Florida Keys, with plush bedding, designer toiletries, world-class concierge staff, and access to the best restaurants and spa treatments, Travelocity has everything you need. You can live it up like the rich and famous in a luxury hotel in Florida Keys with discounts and offerings from Travelocity. Now you can have all the luxury perks you want, and stay on the cheap. So live it up! A luxury hotel in Florida Keys can whisk you away without breaking the bank.

Florida Keys hotels essential information

Accommodation	8,215 hotels
Lowest Price	CA $151
Highest Price	CA $627
Popular hotels	Little Palm Island Resort & Spa - A Noble House Resort, Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Cheeca Lodge & Spa, Casa Marina Key West, Curio Collection by Hilton, Kingsail Resort, Southernmost Beach Resort, Parmer's Resort, H2O Suites - Adults Only, Seashell Motel & Key West Hostel, Playa Largo Resort & Spa, Autograph Collection, The Mansion on the Sea - Southernmost House in the USA