Book a hotel near Santee, South Carolina

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Hotels near Santee

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Free cancellation
Reserve now, pay when you stay
0.42 km from city centre
The price is CA $144 per night
CA $144
CA $159 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Free cancellation
Reserve now, pay when you stay
0.41 km from city centre
The price is CA $103 per night
CA $103
CA $114 total
Dec 28 - Dec 29
includes taxes & fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Breakfast included
Pet-friendly
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
Free cancellation
Reserve now, pay when you stay
0.96 km from city centre
The price is CA $180 per night
CA $180
CA $200 total
Jan 22 - Jan 23, 2026
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy Santee SC
Free cancellation
Reserve now, pay when you stay
1.01 km from city centre
The price is CA $165 per night
CA $165
CA $184 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
Free cancellation
Reserve now, pay when you stay
0.28 km from city centre
The price is CA $141 per night
CA $141
CA $156 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
Free cancellation
0.27 km from city centre
The price is CA $137 per night
CA $137
CA $152 total
Dec 28 - Dec 29
includes taxes & fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Pet-friendly
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Free cancellation
Reserve now, pay when you stay
0.9 km from city centre
The price is CA $162 per night
CA $162
CA $179 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway Santee SC
Free cancellation
Reserve now, pay when you stay
0.22 km from city centre
The price is CA $74 per night
CA $74
CA $90 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
Free cancellation
Reserve now, pay when you stay
1.18 km from city centre
The price is CA $83 per night
CA $83
CA $93 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Breakfast included
Pet-friendly
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
Free cancellation
Reserve now, pay when you stay
0.27 km from city centre
The price is CA $96 per night
CA $96
CA $106 total
Dec 28 - Dec 29
includes taxes & fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Breakfast included
Pet-friendly
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street Santee SC
0.73 km from city centre
The price is CA $109 per night
CA $109
CA $121 total
Dec 31 - Jan 1, 2026
includes taxes & fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Breakfast included
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive Santee SC
0.25 km from city centre
Get rates
Stay at this vacation home in Santee. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Santee Cooper Country Club and Santee National Golf Club are located nearby.
Pool
Kitchen
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee hotels essential information

Accommodation
302 hotels
Lowest Price
CA $90
Highest Price
CA $200
Popular hotels
Tru By Hilton Santee, Baymont by Wyndham Santee, Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee, Comfort Inn & Suites Santee, Holiday Inn Santee by IHG, Best Western Plus Santee Inn, Quality Inn & Suites, Travelodge by Wyndham Santee, Red Roof Inn Santee, Ramada by Wyndham Santee I-95, Wyndham Vacation Resorts Lake Marion

Recent Santee hotel reviews by fellow wanderers

Tru By Hilton Santee

Tru By Hilton Santee

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Clean and bright. They have an area in the lobby with pool table and a few cubby holes of wooden blocks and board games for the kids. Remember Candy Land? Also, separate area off the lobby for quiet computer use. Very satisfying after a long time driving. "
A verified traveller stayed at Tru By Hilton Santee
Tru By Hilton Santee

Types of hotels

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Areas of Santee