Book Cheap Hotels in Southern Minnesota
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check hotel availability in Southern Minnesota
Most frequently booked Southern Minnesota hotels

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Free cancellation
Reserve now, pay when you stay
123.79 km from city centre
The price is CA $226 per night
CA $226
CA $261 total
May 22 - May 23
includes taxes & fees
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mayo Civic Center and Shops University Square are located nearby.
Pool
Hot tub

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Free cancellation
Reserve now, pay when you stay
124.02 km from city centre
The price is CA $114 per night
CA $114
CA $131 total
Jun 1 - Jun 2
includes taxes & fees
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Olmsted County Fairgrounds are located nearby.
Pool
Hot tub

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Free cancellation
Reserve now, pay when you stay
123.62 km from city centre
The price is CA $212 per night
CA $212
CA $244 total
May 25 - May 26
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mayo Civic Center and Shops University Square are located nearby.
Pool
Breakfast included

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Free cancellation
Reserve now, pay when you stay
123.82 km from city centre
The price is CA $144 per night
CA $144
CA $166 total
May 31 - Jun 1
includes taxes & fees
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Shops University Square are located nearby.
Pool
Hot tub

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Free cancellation
124.04 km from city centre
The price is CA $160 per night
CA $160
CA $188 total
May 30 - May 31
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Rochester Public Library are located nearby.
Pet-friendly
Free WiFi

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw, Rochester, MN
Free cancellation
Reserve now, pay when you stay
122.64 km from city centre
The price is CA $134 per night
CA $134
CA $154 total
May 30 - May 31
includes taxes & fees
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Mayo Civic Center and Soldiers Field Veterans Memorial are located nearby.
Pool
Hot tub

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Free cancellation
Reserve now, pay when you stay
122.24 km from city centre
The price is CA $112 per night
CA $112
CA $129 total
May 25 - May 26
includes taxes & fees
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mayo Civic Center and Cascade Lake Beach are located nearby.
Pool
Hot tub

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
161 13th Ave Sw, Rochester, MN
Free cancellation
Reserve now, pay when you stay
122.34 km from city centre
The price is CA $138 per night
CA $138
CA $159 total
May 30 - May 31
includes taxes & fees
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mayo Civic Center and Cascade Lake Beach are located nearby.
Pool
Free WiFi

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Free cancellation
Reserve now, pay when you stay
124.55 km from city centre
The price is CA $99 per night
CA $99
CA $114 total
May 26 - May 27
includes taxes & fees
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Mayo Civic Center and Marcus Rochester Cinema are located nearby.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Southern Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southern Minnesota with star rating
Check Southern Minnesota hotel room prices by star rating

4 Star Hotels
4 properties
Top family friendly Southern Minnesota hotel deals

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw, Rochester, MN
The price is CA $112 per night from May 25 to May 26
CA $112
CA $128 total
May 25 - May 26
includes taxes & fees
8/10 Very Good! (606 reviews)
Top cheap Southern Minnesota hotel deals

Red Carpet Inn Rochester
2214 South Broadway, Rochester, MN
The price is CA $84 per night from May 24 to May 25
CA $84
CA $96 total
May 24 - May 25
includes taxes & fees
7.6/10 Good! (514 reviews)
Top hotels in Southern Minnesota for Extended Stay

The Berkman
217 14th Ave SW, Rochester, MN
The price is CA $149 per night from May 31 to Jun. 1
CA $149
CA $173 total
May 31 - Jun 1
includes taxes & fees
9.6/10 Exceptional! (292 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southern Minnesota hotels essential information
Accommodation | 1,149 hotels |
---|---|
Lowest Price | CA $82 |
Highest Price | CA $226 |
Popular hotels | Kahler Grand Hotel, AmericInn by Wyndham Rochester Near Mayo Clinic, Kahler Inn and Suites - Mayo Clinic Area, Hyatt House Rochester/Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area by IHG, SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys, Med City Inn & Suites - Mayo Clinic Area, Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys, La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S |
Recent Southern Minnesota hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The staff and owners here are great!! We had one small problem with water pressure in our room. It was taken care of immediately with a brand new shower head. This is always my go to hotel for my appointments at Mayo Clinic."
A verified traveller stayed at La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hotels near…
Hotels by star rating
Areas of Southern Minnesota
Most popular
Hotels
Hotels closest to Minnesota State FairgroundsOahu All Inclusive Resorts & HotelsMinneapolis Kid Friendly HotelsKauai All Inclusive Resorts & HotelsCheap Hotels in HermantownHotels closest to Paul Bunyan State ForestHotels closest to Black Bear CasinoBloomington Hotels with Hot TubsMaui All Inclusive Resorts & HotelsHotels closest to Twin Cities Premium OutletsUpstate New York Golf Resorts & HotelsCheap Hotels in KauaiCheap Hotels in MinneapolisCheap Hotels in BloomingtonCheap Hotels in MauiUpstate New York Waterpark Hotels and ResortsMinneapolis Hotels with Hot TubsCheap Hotels in Oahu
Activities