Book spa resorts in Downtown San Francisco, San Francisco from CA $175

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Downtown San Francisco Spa Resorts & Hotels

Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $587 per night
CA $587
CA $691 total
Jun 13 - Jun 14
includes taxes & fees
Stay at this 5-star luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
Hotel Nikko San Francisco

Hotel Nikko San Francisco

4.5 out of 5
222 Mason St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $248 per night
CA $248
CA $355 total
May 26 - May 27
includes taxes & fees
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, a nightclub, and a rooftop terrace. Our guests praise the breakfast and the pool in our ...
The Donatello

The Donatello

3.5 out of 5
501 Post St, San Francisco, CA
Get rates
Stay at this 3.5-star business-friendly hotel in San Francisco. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and ...
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5 out of 5
757 Market St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $580 per night
CA $580
CA $683 total
May 24 - May 25
includes taxes & fees
Stay at this 5-star luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our ...
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

5 out of 5
600 Stockton St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $472 per night
CA $472
CA $623 total
May 24 - May 25
includes taxes & fees
Stay at this 5-star luxury hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
The St. Regis San Francisco

The St. Regis San Francisco

5 out of 5
125 3rd St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $566 per night
CA $566
CA $667 total
May 24 - May 25
includes taxes & fees
Stay at this 5-star luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff ...
InterContinental San Francisco by IHG

InterContinental San Francisco by IHG

4 out of 5
888 Howard Street, San Francisco, CA
Free cancellation
The price is CA $201 per night
CA $201
CA $294 total
May 23 - May 24
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful ...
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $367 per night
CA $367
CA $432 total
May 30 - May 31
includes taxes & fees
Book a stay at this historic hotel in San Francisco. Enjoy 2 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and ...
W San Francisco

W San Francisco

4.5 out of 5
181 3rd St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $225 per night
CA $225
CA $314 total
May 23 - May 24
includes taxes & fees
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
501 Geary St, San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $225 per night
CA $225
CA $264 total
May 21 - May 22
includes taxes & fees
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St., San Francisco, CA
Free cancellation
Reserve now, pay when you stay
The price is CA $175 per night
CA $175
CA $264 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Huntington Hotel

Huntington Hotel

4.5 out of 5
1075 California St, San Francisco, CA
Get rates
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the property condition ...
Don't see what you're looking for?
See all available properties in Downtown San Francisco
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Downtown San Francisco hotels essential information

Accommodation
871 hotels
Lowest Price
CA $175
Highest Price
CA $587
Popular hotels
Huntington Hotel, Hotel Nikko San Francisco, InterContinental San Francisco by IHG, Palace Hotel, a Luxury Collection Hotel, San Francisco, The Donatello, W San Francisco, Hilton San Francisco Union Square, Four Seasons Hotel San Francisco at Embarcadero, Four Seasons Hotel San Francisco, The Ritz-Carlton, San Francisco, The Marker Union Square San Francisco, The St. Regis San Francisco

Recent Downtown San Francisco hotel reviews by fellow wanderers

Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Excellent as always"
A verified traveller stayed at Hyatt Regency San Francisco
Hyatt Regency San Francisco