Book Cheap Hotels in South San Diego
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Most frequently booked South San Diego hotels

Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Free cancellation
Reserve now, pay when you stay
23.52 km from city centre
The price is CA $159 per night
CA $159
CA $183 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Hot tub

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
Free cancellation
Reserve now, pay when you stay
22.34 km from city centre
The price is CA $171 per night
CA $171
CA $246 total
Jan 2 - Jan 3, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Hot tub

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free cancellation
Reserve now, pay when you stay
19.63 km from city centre
The price is CA $142 per night
CA $142
CA $165 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Free WiFi

Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
Free cancellation
Reserve now, pay when you stay
23.17 km from city centre
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Pool
Hot tub

Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
Free cancellation
19.76 km from city centre
The price is CA $165 per night
CA $165
CA $192 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Pet-friendly

Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
Free cancellation
Reserve now, pay when you stay
22.79 km from city centre
The price is CA $167 per night
CA $167
CA $192 total
Jan 3 - Jan 4, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Pool
Hot tub

The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
Free cancellation
Reserve now, pay when you stay
27.99 km from city centre
The price is CA $190 per night
CA $190
CA $246 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Bay and Port of San Diego are located nearby.
Pool
Hot tub

Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
Free cancellation
Reserve now, pay when you stay
21.16 km from city centre
The price is CA $313 per night
CA $313
CA $359 total
Dec 30 - Dec 31
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Pool
Pet-friendly

DoubleTree by Hilton Hotel San Diego - Mission Valley
7450 Hazard Center Dr San Diego CA
Free cancellation
Reserve now, pay when you stay
23.51 km from city centre
The price is CA $154 per night
CA $154
CA $177 total
Jan 3 - Jan 4, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Pool
Hot tub
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See all available properties in South San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top family friendly South San Diego hotel deals

El Primero Hotel
416 Third Avenue Chula Vista CA
The price is CA $116 per night from Dec 28 to Dec 29
CA $116
CA $127 total
Dec 28 - Dec 29
includes taxes & fees
9.2/10 Wonderful! (943 reviews)
Top cheap South San Diego hotel deals

The Rambler
225 Bay Blvd Chula Vista CA
The price is CA $130 per night from Jan 12 to Jan 13
CA $130
CA $151 total
Jan 12 - Jan 13, 2026
includes taxes & fees
9/10 Wonderful! (2,011 reviews)
Top hotels in South San Diego for Extended Stay

City24 Hotel Little Italy Mission Hills
2801 India St San Diego CA
9.6/10 Exceptional! (108 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South San Diego hotels essential information
Accommodation | 7,784 hotels |
|---|---|
Lowest Price | CA $101 |
Highest Price | CA $430 |
Popular hotels | Bay Club Hotel & Marina, Sheraton San Diego Resort, The DEXTRO Little Italy, BW Premier Collection, Legacy Resort Hotel & Spa, Courtyard by Marriott San Diego Downtown Little Italy, Hilton San Diego Mission Valley, The Dana on Mission Bay, Lafayette Hotel & Club, DoubleTree by Hilton Hotel San Diego - Mission Valley |
Recent South San Diego hotel reviews by fellow wanderers

Courtyard by Marriott San Diego Downtown Little Italy
5 out of 5
Posted 14 hours ago
Travelocity Verified Review
"Excellent "
A verified traveller from Atlanta stayed at Courtyard by Marriott San Diego Downtown Little Italy
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